..Information to Pharmacists
    _______________________________

    Your Monthly E-Magazine
    JUNE, 2003

    Published by Computachem Services

    P.O Box 297.
    Alstonville. 2477
    NSW Australia

    Phone:
    61 2 66285138

    E-Mail
    This
    Page
    Click For a
    Printer-Friendly
    Page
    Bookmark
    This Page

    ANDREW SNOW

    Compounding Pharmacist Perspective

    Acne Treatment

    Today, there are hundreds of treatment options for acne. It is a massive market for most teenagers, which can be seen by the large amount of advertising for brands such as Clearasil.

    From my experiences so far, I have found that most of the commercial products are not the most effective products available.
    I find it very interesting that some of the local dermatologists have very little faith in very popular products such as Benzac that has been around for years, due to factors such as resistance.
    It is some of the more simple preparations without extra additives that seem to have a greater chance of being effective.
    For instance, some of the creams available have are quite thick with various chemicals contained in them, with a higher probability of clogging up pores, which could result in the acne getting worse.
    That’s why, I believe some of the simple products have more chance of being effective because there is less chance the skin will become irritated.
    For example, even using a simple moisturiser such as plain sorbolene cream (or something similar) can be a great option.

    One of the first line treatments applied by one local dermatologist is Chlorhexidine with Salicylic acid in an alcohol base which can be given out without a prescription.
    This aims to kill off any bacteria, and clear out the pores.
    If this is shown not to be extremely effective, Clindamycin solution can be quite effective as a local antibiotic treatment.
    Again, this is done in an alcohol base because this can help clear out the pores further, where a cream can clog up pores.
    Clindamycin appears to have less resistance than standard preparations on the market such as Erycane.

    To help rejuvenate the skin, Glycolic Acid in many different strengths can be used.
    This can be put in many different bases such as aqueous cream or cetaphil lotion.
    This works by bringing the lower layers of skin to the surface to help minimise any scarring from acne

    For more serious treatment, Tretinoin can be a very effective treatment.
    This can be made into a gel or cream in several strengths.
    It has many benefits to Roacutane because there are minimal systemic side effects, although care must be taken for the face.
    The compounded forms have many benefits to the manufactured forms because they can be made to any strength, so if a stronger dose is needed, it can be easily made.
    Also, unlike Isotrex gel (with the active ingredient Isotretinoin), compounding chemists can use Tretinoin, which has been shown to be more effective.

    Various plans have been formulated, and one of the most effective treatment plans that I have witnessed would include using Tretinoin gel from 0.025%-0.05% at night to the affected areas, then Glycolic Acid 5-10% in Cetaphil in the morning.
    Initially, the glycolic acid should be applied at a lower strength and washed off after ten to fifteen minutes otherwise the skin can burn.
    After a while, it can be left on all day.
    There is a chance that the skin can become quite dry, and plain sorbolene cream would definitely be sufficient to keep the skin looking respectable.


    Back to Front Page